Panama City

Nuestra Señora de La Asuncion de Panama

Founded in 1519, Nuestra Señora de la Asunción de Panamá (Panama City) was the first European settlement on the Pacific Coast of the Americas. The outpost quickly became the capital of Castilla de Oro, a base for Pizarro’s campaign against the Inca Empire and a collection point for treasure bound for Spain. That wealth attracted trouble, culminating in Henry Morgan’s notorious raid of 1671.

Two years later, the city was reestablished five miles southwest on a defensible peninsula now known as the Casco Antiguo. This quarter, with its narrow streets, colonial facades, and restored plazas, is today a UNESCO World Heritage Site. Once the wealthiest city in the New World, Panama’s fortunes shifted over centuries, but its geography has kept it central to global trade—from the California Gold Rush to the Panama Canal and into the present day.

Modern Panama City is the region’s most cosmopolitan hub. High-rises line the waterfront, luxury shopping and fine dining abound, and the city serves as a jumping-off point for rainforests, islands, and Pacific beaches. Its mix of history, culture, and modern convenience makes it a natural base for exploring Panama.

What to do in Panama City

  • Exploring Casco Antiguo
  • Visiting the ruins of Old Panama
  • Museum tours
  • Dining & nightlife
  • Jazz clubs & live music
  • Canal day trips
  • Birdwatching
  • Pearl Islands boat trips

What is the Weather Like?

Panama City is warm year-round, with average highs in the upper 80s and lows near 75°F. Rain is most common from May to November, with October typically the wettest month. The dry season, December through March, brings steady sunshine and clearer skies.

Getting There

Panama City is served by Tocumen International Airport (PTY), the region’s primary hub, located about 40 minutes from downtown. Albrook (Marcos A. Gelabert) Airport, just 15 minutes from the city center, offers domestic connections to more than a dozen destinations, with flight times under one hour.

Start your journey today

LANDED delivers the finest in custom, private travel to Central America, South America, and Antarctica. These regions are our passion; we know them first-hand and by heart. Speak with one of our travel designers and let us create a tailored itinerary for you in Panamá.

How to combine Panama City

Have some extra time? Here are some options for you to combine with.